Giovanni Martinelli

Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (I.R.S.T.) Meldola - FC, IT Education (Laurea or other professional education, include post doctoral training) First Degree: Graduated in Medicine Name of Institution: University of Verona Medical School City, Country: Verona, Italy Date: 1985 University of Verona Verona, Italy in 1988 Hematology University of Verona Verona, Italy in 1992 Medical Genetics Registration medical register (Verona Italy): year 1986, n° 4900. 20 July 2001 Suitable to the role of Associate University Professor, scientific field disciplinary F07G – Malattie del Sangue, on the Facoltà di Medicina e Chirurgia dell’Università degli Studi di Milano. Research and/or professional experience List, in chronological order, present and previous employment, experience, certifications, and honors. Include present membership on any Governmental or Advisory Committee/Boards. January 1984-1988 Research and clinical training as Resident Physician, Institute of Medical Pathology (Division of Hematology, University of Verona Medical School). The main scientific interest regarded the field of hematological malignancies, in particular leukemias and lymphomas. During this period he learned patient management and diagnosis, the monitoring of infections and therapy in immunocompromised patients. He performed and monitored autologous bone marrow transplantation in neoplastic patients, immunotyped bone marrow cells with monoclonal antibodies, and determined levels of interferon and interleukins in patients samples. June 1988-November 1988 Specialist in Hematology, U.S.L. 31, District of Mantova City, Italy, and U.S.L. 29, District of Volta Mantovana, Italy. 1989 Specialist in General Hematology, U.S.L. 47, Mantova, Italy. 1990-1991 Research and clinical training, Institute of Biological Sciences, University of Verona. 1991-1993 Research and clinical training, Institute of Hematology and Oncology “Seràgnoli”, University of Bologna. January 1993 - 2005 Medical Doctor for Prof. Sante Tura and Prof. Michele Baccarani, Institute of Hematology \"L. e A. Seràgnoli\", University of Bologna Medical School. Responsible of the Laboratory of Molecular Biology. Main fields of research: acute leukemia, chronic myeloid leukemia: research of target therapies in the major haematological syndromes: therapy of acute leukemias, therapy of chronic myeloid leukemias Ph+ and not Ph+, and therapy of Hypereosinophilic syndrome (HES). 2005 - 2017 Associate Professor in Hematology –, Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna. Responsible of the Laboratory of Molecular Biology, Institute of Hematology “L. and A. Seràgnoli”. Main fields of research: acute leukemia, chronic myeloid leukemia: research of target therapies in the major haematological syndromes: therapy of acute leukemias, therapy of chronic myeloid leukemias Ph+ and not Ph+, and therapy of Hypereosinophilic syndrome (HES). Clinical Activity: Conduction of several Phase I, Phase II, and Phase III clinical trials on AML, LAL, and CML as Principal Investigator; Studies with compassionate use of drugs with good knowledge of Good Clinical Practice. From 1st January 2018 – present Scientific Director - Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) Srl – IRCCS, Meldola (FC), Italy Research interests His research and clinical activity involve the area of acute and chronic myeloid leukemia (AML and CML), acute lymphoblastic leukemia (ALL) and myelodisplastic syndromes (MDS). Expertise: Conduction of several Phase I-II-III clinical trials and biological research projects on AML, ALL, MDS and CML as Principal Investigator, with good knowledge of Good Clinical Practice. He has the skills, expertise and authority to lead a team and he has the capacity of using the resources in a flexible way, to achieve the project objectives. Association Membership - Società Italiana di Ematologia Sperimentale (SIES) Member and Vice President of the Consiglio Direttivo SIES - Società Italiana di Ematologia (SIE) - American Society of Haematology (ASH) - American Association for the Advancement of Sciences (AAAS) - American Association for Cancer Research (AACR) - European Haematology Association (EHA) - American Society of Clinical Oncology (ASCO) - European Association for Cancer Research (EACR) - European LeukemiaNet (Progetto Europeo VI PQ) - Gruppo Italiano Malattie Ematologiche dell’Adulto (GIMEMA) Working Party Leucemie Acute - COST Action BM0801 (EuGESMA) Reviewing Activities - Haematologica - Leukemia - Blood - American Journal of Hematology - Clinical Leukemia - Cancer - Hematological Oncology - Neoplasia - Annals of Hematology - Editor-in-Chief: Hematology Reports Projects & Achievements: Co-operator in the following Research projects: MURST - COFIN 2001 – 2002 – 2003; Ricerca fondamentale orientata 2002 – 2003; Principal proposed in the RFO 60% 2007 and 2008; FIRB 2001 – 2003 projects. Scientific Responsible in the FIRB 2006 project. Principal Investigator AIRC Grant Proposal 2004, AIRC 2007, AIRC 2010. Responsible for Research Unit of PRIN 2008 project; Scientific Responsible of two projects on Bando Ministero Salute 2009, and one project on Bando Ministero Salute Ricerca Finalizzata 2009. FP7-HEALTH-2012-INNOVATION-1 Seventh framework programme 2011 Proponent and Principal Investigator of financed International project: “Next Generation Sequencing platform for targeted Personalized Therapy of Leukemia - NGS-PTL”. Principal Investigator of the AIRC Investigator Grant (IG Grant) 2016 “Beating aneuploid acute leukemia by integrated genomic, functional and preclinical studies”. Innovative Medicine Initiative 2 (IMI2) Responsible of Work Package (WP Leader) in the financed International project: “Healthcare Alliance for Resourceful Medicines Offensive against Neoplasms in Hematology – HARMONY” (January 2017). EraPerMed Initiative -WP LEADER WP4 of Erapermed Project SYNTHERAPY: “Synthetic Lethality for Personalized Therapy-based Stratification In Acute Leukemia” (2018) H2020 -WP LEADER of H2020 project ONCORELIEF (2019)