Matthias Barton

Matthias Barton, MD, is a physician and professor of cardiology at the University of Zurich in Switzerland. His clinical and investigative focus are cardiovascular and preventive medicine, with a particular interest in coronary artery disease and heart disease in women. Barton has studied vascular factors and receptors involved in chronic non-communicable diseases for more than 30 years. In the 1990s he was involved in the preclinical development of endothelin receptor antagonists (ERAs) for the treatment of cardiovascular and chronic kidney diseases (CKD). Together with Dr. Anthony Davenport, Barton co-chaired the Twelfth International Conference on Endothelin (ET-12) in Cambridge in 2011, and in the same year together with Dr. Donald Kohan edited the first book on «Endothelin in Renal Physiology and Disease» also discussing the therapeutic potential of ERAs in CKD. Barton subsequently participated in clinical trials investigating endothelin receptor agonists for the treatment of CKD. In 2019, together with Dr. Masashi Yanagisawa, he published a comprehensive review discussing the role of endothelin in health and disease and clinical studies using ERAs.