Raffaella Fabbri

In 1977 Raffaella Fabbri obtained the DEGREE in Biological Sciences, University of Bologna, Italy. Since 1977 she has been involved in many Scientific Activities which are well-documented by 349 ATICLES published in Italian and Foreign Journals. Beginning on April 18 1977 she has been working as a BIOLOGIST in the Human Reproductive Medicine Unit, Department of Gynecology, Obstetrics and Pediatric Science, S.Orsola Hospital, University of Bologna, Italy. Since 1980 to 1999 she participated in the CNR RESEARCH PROJECT. Since 1988 to 2003 she participated in the RESEARCH PROGRAM EX-60% University of Bologna Italy. She participated in the NATIONAL RESEARCH PROGRAM EX-40% University of Bologna, Italy in 2003 “Optimization of freezing/thawing and human ovarian cortex culture techniques with the aim of restoring fertility in oncological patients.” In 2001 she realized a NATIONAL and INTERNATIONAL WORLDWIDE PATENT about Method and Solution for cryopreserving oocytes (Application No PCT/IT01/00139). In 2006 she obtained the United States Patent US 7,011,937 B2 for Method and solutions for cryopreserving oocytes. In 2001 she realized an ATLAS entitled “Human oocyte and embryo Atlas” In 2011 she realized an ATLAS entitled “Atlas of Human oocyte and embryo” From 2001 to 2002 she has been ASSOCIATE EDITOR for HUMAN REPRODUCTION JOURNAL, OXFORD UNIVERSITY. Since 2003 she is REVIEWER for HUMAN REPRODUCTION JOURNAL. In 2003 she realized a CD entitled “HUMAN OOCYTE CRYOPRESERVATION.” In 2003 she realized a WEB-SITE www.astroonlus.it regarding the human ovarian tissue cryopreservation. Since January 2004 she is RESEARCHER of the University of Bologna, Italy, in Human Reproductive Medicine Unit. Since 2002 she was involved in HUMAN OVARIAN TISSUE CRYOPRESERVATION AND TRANSPLANTATION . In 2018 she obtained the first Italian birth after cryopreserved ovarian tissue transplantation in patient affected by non Hodgkin’s lymphoma, and a second one in 2019 in a hodgkin lymphoma patient. To date, together her group, she performed 27 transplantations (eterotopic and orthotropic) with a pregnancy rate of 42%. The RESEARCH TOPICS: 1) Cocultures of human granulosa cells and sperms. 2) Cocultures of human granulosa cells, fertilization and embryonal development (Blastocysts). 3) In vitro evaluation of the effects of GNRH on follicular steroidogenesis. 4) Evaluation of Insulin Like Growth Factor (IGFII) effects on human cryopreserved ovarian tissue culture. 5) Cryopreservation of oocytes, embryos and blastocysts. 6) Assisted hatching. 7) Cryopreservation of immature oocytes. 8) Correction of polyspermy through pronucleus extraction and subsequent embryonal development. 9) In vitro maturation, fertilization and development of oocytes recovered from untreated normal and polycystic ovarian patients. 10) Cryopreservation of Human mature oocytes. 11) Human ovarian tissue cryopreservation and in vitro maturation of ovarian follicles.