Mev Dominguez-Valentin

Mev Dominguez-Valen1n (MDV), PhD is a Scien1st the Department of Tumor Biology of the Ins1tute for Cancer Research from Oslo University Hospital (Norway). She is the Principal Inves1gator of the largest database in Lynch Syndrome (PLSD) that aims to facilitate personalized precision medicine for Lynch syndrome. MDV has had extensive mobility throughout her career, with ac1vity across many countries, and even two con1nents. Her main research areas include Lynch syndrome (LS) and the large prospec1ve observa1onal studies that have recently increased understanding of the effec1veness of colonoscopic surveillance and the heterogeneity of cancer risk between genotypes. Also, the use of mul1gene panel tes1ng in familial cancer cases without gene1c cause demonstrated by single gene tes1ng, to gain informa1on on to which degree other genes may have been causa1ve for cancer in the pa1ents and their rela1ves, and to be informed on how such genes were deranged to discriminate between normal and diseasecausing variants. MDV is also interested in unravelling the challenges of implemen1ng the advances in diagnosis of hereditary cancer suscep1bility and applying these insights to clinical prac1ce in La1n America. In addi1on, MDV have established na1onal and interna1onal collabora1ons in LS that have been crucial, especially in genera1ng knowledge about mismatch repair genes variant classifica1on and sharing of gene1c prac1ces within the region. MDV pursues her interest in the gene1c epidemiology of hereditary cancers in low-resource seRng in Peru. At educa1onal and mentoring level, MDV is co-founder of the Research Experience for Peruvian Undergraduates Program (REPU), ac1ve mentor of the interna1onal mentoring program in Peru and ac1vely promotes the research of Peruvian scien1sts in Europe (SINAPSIS). MDV is the Program director of the European Hereditary Tumor Group (EHTG), Ambassador at the North American Group (CGA) and Scien1fic advisor of the La1n America Group of the Hereditary Tumors (LA-GETH).