Dr. Marc A. Pfeffer, a graduate of Rockford College in Rockford, Illinois, received both his doctorate in physiology and biophysics and his medical degree from the University of Oklahoma in Oklahoma City. He completed his internship, residency and clinical fellowship at the Peter Bent Brigham Hospital, Harvard Medical School in Boston. Dr. Pfeffer is currently the Distinguished Dzau Professor of Medicine at Harvard Medical School, and Senior Physician in the Cardiovascular Division at the Brigham and Women’s Hospital in Boston. A noted researcher, Dr. Pfeffer, along with his late wife, Dr. Janice Pfeffer, and Eugene Braunwald MD, is credited with introducing the concept that angiotensin-converting enzyme inhibitors (ACEIs) could attenuate adverse ventricular remodelling following myocardial infarction and that this use would result in a prolongation of survival and other clinical benefits. Since this initial discovery, he has had a principal role in several practice-changing clinical outcome trials. He is well known for exploring the interfaces between renal and cardiovascular diseases. An internationally recognized expert in the field of cardiology, Dr. Pfeffer was recognized by Science Watch as having the most ‘Hot Papers’ (highly cited) in all of clinical medicine and was listed as one of the highly influential biomedical researchers of 1996-2011 in the European Journal of Clinical Investigation. He is the recipient of the William Harvey Award of the American Society of Hypertension, the Okamoto Award from Japan’s Vascular Disease Research Foundation, the Clinical Research Prize, the James B. Herrick Award and the 2023 Eugene Braunwald Academic Mentorship Award of the American Heart Association. The Distinguished Scientist Awards from both the American Heart Association as well as the American College of Cardiology. The Lifetime Achievement Award from both the Heart Failure Society of America and the Heart Failure Association of the European Congress of Cardiology. The Gold Medal Award from the European Society of Cardiology in 2018. Dr. Pfeffer has Honorary Doctoral Degrees from Sahlgrenska Academy at the University of Gothenburg, Sweden, from the University of Glasgow, Scotland, from UCLouvain University in Belgium, and from Semmelweis University, Budapest, Hungary. He is a Fellow of the British Society for Heart Failure as well as an Honorary Fellowship of the Royal College of Physicians, London.